Axor Biosystems has revolutionized biological sample preparation by releasing a groundbreaking, miniaturized preparative-electrophoresis-in-a-microplate system (PEM) that dramatically reduces both cost and complexity for purification and QC of reactions products. 

The system integrates 5 reaction purification and QC steps in 1 consumable: 

1. Molecular reactions such as ligations

2. Separation of the reaction products

3. Determination of the molecular weights of all the product constituents

4. Purification of specific constituents by precise molecular weights

5. Accurate quantitation

The above steps are performed in parallel for up to 96 samples in 15-30 minutes.

Purification and QC analysis can be performed on DNA reactions, for example, transposase-based NGS library preps, or on protein preparations, for example, in vitro transcription-translation reactions.

Benefits

Current reaction cleanup and QC workflows are laborious, require long process times, with high inventory and disposal costs.  The Axor system reduces this complexity providing

1. 10x automation efficiency gain

The typical 20+ pipetting operations required for purifying reaction products by column- or bead-based approaches on a liquid-handling robot are reduced to just 2 pipetting operations, substantially reducing operational overheads, liquid and plastic waste, hands-on interventions and data management and sample tracking burdens.

2. 10x throughput increase

Run times are reduced from  the typical 360+ mins to < 30 mins enabling the processing of 10x more samples per unit time resulting in substantial efficiency and cost benefits.

3. Enhanced Precision

The Axor system uses high-resolution electropheresis based purification ensuring consistent separation and purification, minimizing variability, and enabling the purification of even closely related species. Metrics that are challenging to achieve with binding-based purification methods.